Echo: The Complete Edition, by Terry Moore, 590 pages.
Julie is going to be divorced soon and wanders out into the wilderness around Moon Lake to get some peace and take some photos. It turns out that she is in the wrong place at the wrong time as a disagreement between Foster, the evil head of a nanotechnology / weapons research group, and Annie, the non-evil inventor of the tech, leads to a nuclear explosion. Julie is transformed by the event, as is a nearby crazed drifter. Annie's boyfriend, Dillon, eventually joins forces with Julie, maybe-not-quite-dead Annie, and Ivy, a freelance operative, to try and stop Foster from misusing the new tech and ending the world. It's a relatively long and complicated graphic novel, but the story is well told and the art supports the story. A good read.